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Symbol
Name
ID
Tank
TRAF family member-associated Nf-kappa B activator
MGI:107676
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
increased B cell proliferation
spleen hyperplasia
increased mature B cell number
increased plasma cell number
increased IgA level
increased IgG1 level
increased IgG2a level
increased IgG2b level
increased IgM level
abnormal macrophage physiology
lymph node hyperplasia
abnormal dendritic cell physiology
abnormal plasmacytoid dendritic cell physiology
increased interferon-alpha secretion
increased interleukin-6 secretion
increased tumor necrosis factor secretion
increased anti-nuclear antigen antibody level
increased anti-double stranded DNA antibody level
liver inflammation
glomerulonephritis
lung inflammation
Availability Mouse Genotype
Tanktm1Aki/Tanktm1Aki

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory