Symbol Name ID |
Tank
TRAF family member-associated Nf-kappa B activator MGI:107676 |
Darker colors indicate more annotations |
Mouse Phenotypes | increased B cell proliferation |
spleen hyperplasia |
increased mature B cell number |
increased plasma cell number |
increased IgA level |
increased IgG1 level |
increased IgG2a level |
increased IgG2b level |
increased IgM level |
abnormal macrophage physiology |
lymph node hyperplasia |
abnormal dendritic cell physiology |
abnormal plasmacytoid dendritic cell physiology |
increased interferon-alpha secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
liver inflammation |
glomerulonephritis |
lung inflammation |
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Availability | Mouse Genotype | |||||||||||||||||||||
Tanktm1Aki/Tanktm1Aki |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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